*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DG3100500 CHEMICAL NAME : Benzoic acid, 3-(aminosulfonyl)-4-benzyl-5-(butylamino)- CAS REGISTRY NUMBER : 36148-38-6 BEILSTEIN REFERENCE NO. : 2783522 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C18-H22-N2-O4-S MOLECULAR WEIGHT : 362.48 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 3-(Aminosulfonyl)-4-benzyl-5-(butylamino)-benzoic acid * 4-Benzyl-3-n-butylamino-5-sulfamylbenzoic acid * Besunide * pINN *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,1170,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 186 mg/kg TOXIC EFFECTS : Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - other changes in urine composition REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,1170,1973 *** END OF RECORD ***