*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG8969000
CHEMICAL NAME           : Benzoic acid,
                          p-(3-(3-(dimethylamino)propoxy)-1H-indazol-1-yl)-,
                          butyl ester
CAS REGISTRY NUMBER     : 20954-15-8
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H29-N3-O
MOLECULAR WEIGHT        : 363.55
WISWESSER LINE NOTATION : T56 BNNJ BR DVO4& DO3N1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * p-(3-(3-(Dimethylamino)propoxy)-1H-indazol-1-yl)benzoic acid butyl ester
   * ITF 633
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 24,965,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 24,965,1969
 
                            *** END OF RECORD ***