*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DH1422000
CHEMICAL NAME           : Benzoic acid, p-guanidino-,
                          4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H15-N3-O4
MOLECULAR WEIGHT        : 337.36
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Coumarin, 4-methyl-7-hydroxy-, p-guanidinobenzoate
   * p-Guanidinobenzoic acid 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
   * 4-Methylumbelliferone 4-guanidinobenzoate
   * MUGB
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 26,137,1982
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 2 mg/kg
SEX/DURATION            : female 2 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 26,137,1982
 
                            *** END OF RECORD ***