*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DH1980000 CHEMICAL NAME : Benzoic acid, p-hydroxy-, butyl ester CAS REGISTRY NUMBER : 94-26-8 BEILSTEIN REFERENCE NO. : 1103741 REFERENCE : 4-10-00-00375 (Beilstein Handbook Reference) LAST UPDATED : 199701 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C11-H14-O3 MOLECULAR WEIGHT : 194.25 WISWESSER LINE NOTATION : QR DVO4 COMPOUND DESCRIPTOR : Primary Irritant SYNONYMS/TRADE NAMES : * Aseptoform butyl * Butoben * Butyl chemosept * Butyl p-hydroxybenzoate * Butyl paraben * n-Butyl parahydroxybenzoate * Butyl parasept * Butyl tegosept * p-Hydroxybenzoic acid butyl ester * Nipabutyl * Solbrol B * Tegosept B *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 5%/48H REACTION SEVERITY : Mild REFERENCE : JSCCA5 Journal of the Society of Cosmetic Chemists. (Soc. of Cosmetic Chemists, 1995 Broadway, Suite 1701, New York, NY 10023) V.1- 1947- Volume(issue)/page/year: 28,357,1977 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 13200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NEZAAQ Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. (Nippon Eisei Gakkai, c/o Kyoto Daigaku Igakubu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.1- 1946- Volume(issue)/page/year: 28,463,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 230 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation REFERENCE : JSCCA5 Journal of the Society of Cosmetic Chemists. (Soc. of Cosmetic Chemists, 1995 Broadway, Suite 1701, New York, NY 10023) V.1- 1947- Volume(issue)/page/year: 28,357,1977 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 504 gm/kg/12W-C TOXIC EFFECTS : Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81355 No. of Facilities: 753 (estimated) No. of Industries: 6 No. of Occupations: 17 No. of Employees: 3511 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81355 No. of Facilities: 704 (estimated) No. of Industries: 10 No. of Occupations: 32 No. of Employees: 24427 (estimated) No. of Female Employees: 18593 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***