*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DH2040000
CHEMICAL NAME           : Benzoic acid, p-hydroxy-, butyl ester, sodium salt
CAS REGISTRY NUMBER     : 36457-20-2
LAST UPDATED            : 199107
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H13-O3.Na
MOLECULAR WEIGHT        : 216.23
WISWESSER LINE NOTATION : QR DVO4 &-NA-
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Butyl p-hydroxybenzoate sodium
   * Sodium butylparaben
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 950 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 45,260,1956
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 230 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 45,260,1956
 
                            *** END OF RECORD ***