*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DH2429000
CHEMICAL NAME           : Benzoic acid, 4-hydroxy-3-methoxy-,
                          8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester,
                          hydrochloride, endo-
LAST UPDATED            : 198809
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H21-N-O4.Cl-H
MOLECULAR WEIGHT        : 327.84
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * endo-4-Hydroxy-3-methoxybenzoic acid 8-methyl-8-azabicyclo(3.2.1)oct-3-yl 
    ester HCl
   * Phyllalbine hydrochloride
   * Vanilloyltropine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 20,1033,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 20,1033,1965
 
                            *** END OF RECORD ***