*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DH2520700 CHEMICAL NAME : Benzoic acid, 2-hydroxy-5-((4-(((3-methyl-2-pyridinyl)amino)sulfony l)phenyl)azo)- CAS REGISTRY NUMBER : 42753-53-7 BEILSTEIN REFERENCE NO. : 0459871 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C19-H16-N4-O5-S MOLECULAR WEIGHT : 412.45 COMPOUND DESCRIPTOR : Reproductive Effector SYNONYMS/TRADE NAMES : * CH 74A * 2-Hydroxy-5-((4-(((3-methyl-2-pyridinyl)amino)sulfonyl)phenyl)azo)benzoic acid *** HEALTH HAZARD DATA *** ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 7 gm/kg SEX/DURATION : male 35 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 37,539,1988 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 5600 mg/kg SEX/DURATION : male 28 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 37,539,1988 *** END OF RECORD ***