*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DH2528300 CHEMICAL NAME : Benzoic acid, p-hydroxy-, (5-nitrofurfurylidene)hydrazide CAS REGISTRY NUMBER : 965-52-6 BEILSTEIN REFERENCE NO. : 1352180 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C12-H9-N3-O5 MOLECULAR WEIGHT : 275.24 WISWESSER LINE NOTATION : T5OJ BNW E1UNMVR DQ COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * Benzoic acid, 4-hydroxy-, ((5-nitro-2-furanyl)methylene)hydrazide * Diarlidan * Dicoferin * Ercefurol * Ercefuryl * p-Hydroxybenzoic acid (5-nitrofurfurylidene)hydrazide * Nifuroxazid * Nifuroxazide * (Nitro-5' furfurylidene-2') hydroxy-4 benzhydrazide * R.C. 27-109 * RC 30-109 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 6 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 21,287,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Behavioral - antipsychotic Lungs, Thorax, or Respiration - respiratory depression Kidney, Ureter, Bladder - other changes in urine composition REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16,663,1964 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 500 ng/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 157,1,1985 TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 250 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 187,55,1987 *** END OF RECORD ***