*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DH3140000 CHEMICAL NAME : Benzoic acid, p-isopropyl-, 2-(diethylamino)ethyl ester, hydrochloride CAS REGISTRY NUMBER : 34320-72-4 LAST UPDATED : 198806 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C16-H25-N-O2.Cl-H MOLECULAR WEIGHT : 299.88 WISWESSER LINE NOTATION : 2N2&2OVR DY1&1 &GH COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * beta-Diethylaminoethyl cumate hydrochloride * p-Isopropylbenzoic acid 2-(diethylamino)ethyl ester hydrochloride * Isopropylcaine hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 370 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 40,449,1951 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 950 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 40,133,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 78 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 8,934,1953 *** END OF RECORD ***