*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DH3661600
CHEMICAL NAME           : Benzoic acid, 4-methoxy-,
                          (1H-pyrrol-2-ylmethylene)hydrazide
CAS REGISTRY NUMBER     : 113906-09-5
LAST UPDATED            : 199403
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H13-N3-O2
MOLECULAR WEIGHT        : 243.29
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-Methoxybenzoic acid (1H-pyrrol-2-ylmethylene)hydrazide
   * N(sup 4)-(4-Methoxyphenyl)semicarbazone
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 78 gm/kg/13W-I
TOXIC EFFECTS :
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - phosphatases
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - dehydrogenases
REFERENCE :
   CIHPDR Zhongguo Yixue Kexueyuan Xuebao.  Journal of the Chinese Academy of
   Medicine.  (China International Book Trading Corp., POB 2820, Beijing, Peop.
   Rep. China)  V.1-    1979-  Volume(issue)/page/year: 12,452,1990
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1560 gm/kg/13W-I
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - food intake (animal)
   Blood - changes in erythrocyte (RBC) count
REFERENCE :
   CIHPDR Zhongguo Yixue Kexueyuan Xuebao.  Journal of the Chinese Academy of
   Medicine.  (China International Book Trading Corp., POB 2820, Beijing, Peop.
   Rep. China)  V.1-    1979-  Volume(issue)/page/year: 12,452,1990
 
                            *** END OF RECORD ***