*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DH6908500
CHEMICAL NAME           : Benzoic acid, thio-, S-ester with
                          N-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(4-hydro
                          xy- 2-mercapto-1-methyl-1-butenyl)formamide benzoate
                          (ester)
CAS REGISTRY NUMBER     : 299-88-7
LAST UPDATED            : 199806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C26-H26-N4-O4-S
MOLECULAR WEIGHT        : 490.62
SYNONYMS/TRADE NAMES :
   * Bentiamine
   * O,S-Bis(benzoyl)thiamine disulfide
   * DBT
   * Dibenzoylthiamine
   * O,S-Dibenzoylthiamine
   * Thiamine, O,S-dibenzoyl-,
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7480 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   62,123,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2120 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   62,123,1966
 
                            *** END OF RECORD ***