*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DI2350000
CHEMICAL NAME           : Benzo(b)naphtho(2,3-d)thiophene, 6,11-dimethyl-
CAS REGISTRY NUMBER     : 32362-68-8
OTHER CAS REGISTRY NOS. : 33944-31-9
BEILSTEIN REFERENCE NO. : 0205644
REFERENCE               : 4-17-00-00726 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C18-H14-S
MOLECULAR WEIGHT        : 262.38
WISWESSER LINE NOTATION : T D6 B656 LSJ C1 J1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 6,11-Dimethylbenzo(b)naphtho(2,3-d)thiophene
   * 4,9-Dimethyl-2,3-benzthiophanthrene
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 440 mg/kg/11W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   XPHPAW U.S. Public Health Service Publication.  (U.S. Government Printing
   Office, Supt. of Documents, Washington, DC 20402)  No.1-    1950-
   Volume(issue)/page/year: 149,477,1951
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1600 ng/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 292,25,1993
 
TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 1250 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 292,25,1993
 
TYPE OF TEST            : DNA damage
ROUTE OF EXPOSURE       : Administration onto the skin
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 292,25,1993
 
TYPE OF TEST            : Mutation in mammalian somatic cells
ROUTE OF EXPOSURE       : Administration onto the skin
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 292,25,1993
 
                            *** END OF RECORD ***