*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DH6165000
CHEMICAL NAME           : Benzoic acid,
                          4-((1-oxo-3-(4-(2-pyridinyl)-1-piperazinyl)propyl)ami
                          no)-, ethyl ester, dihydrochloride
CAS REGISTRY NUMBER     : 104393-11-5
LAST UPDATED            : 198706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H26-N4-O3.2Cl-H
MOLECULAR WEIGHT        : 455.43
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-((1-Oxo-3-(4-(2-pyridinyl)-1-piperazinyl)propyl)amino)benzoic acid  
   ethyl ester 2HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 419 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 30,13,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 301 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 30,13,1987
 
                            *** END OF RECORD ***