*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DJ2106000
CHEMICAL NAME : 4H-1-Benzopyran-8-acetic acid, 4-oxo-2-phenyl-
CAS REGISTRY NUMBER : 87626-55-9
BEILSTEIN REFERENCE NO. : 4260339
LAST UPDATED : 199612
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C17-H12-O4
MOLECULAR WEIGHT : 280.29
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* Flavone acetic acid
* LM-975
* NSC 347512
* 4-Oxo-2-phenyl-4H-1-benzopyran-8-acetic acid
* 2-Phenyl-8-(carboxymethyl)-benzopyran-4-one
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
12,123,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 280 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IVIVE4 In Vivo. (POB 51359, Kiffisia, GR-145 10, Greece) V.1- 1987-
Volume(issue)/page/year: 6,73,1992
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 392 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
12,123,1987
** MUTATION DATA **
TYPE OF TEST : DNA damage
ROUTE OF EXPOSURE : Intravenous
TEST SYSTEM : Rodent - mouse
DOSE/DURATION : 200 mg/kg
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
48,1279,1988
*** END OF RECORD ***