*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NQ2616666
CHEMICAL NAME           : 4H-1-Benzopyran-4-one,
                          2,3-dihydro-5,7-dihydroxy-8-((dimethylamino)methyl)-2
                          -phenyl-, (S)-
CAS REGISTRY NUMBER     : 183051-59-4
LAST UPDATED            : 199806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H19-N-O4
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (S)-2,3-Dihydro-5,7-dihydroxy-8-((dimethylamino)methyl)-2-phenyl-4H-1-be
     nzopyran-4-one
   * 8-Dimethylaminomethyl pinocembrin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DARUEE Dokl Akad Nauk resp. Uzb.  Volume(issue)/page/year: (9-10),55,1995
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 196 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   DARUEE Dokl Akad Nauk resp. Uzb.  Volume(issue)/page/year: (9-10),55,1995
 
                            *** END OF RECORD ***