*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DJ3100000
CHEMICAL NAME : 2H-1-Benzopyran-2-one, 4-hydroxy-
CAS REGISTRY NUMBER : 1076-38-6
BEILSTEIN REFERENCE NO. : 0129768
REFERENCE : 5-18-01-00378 (Beilstein Handbook Reference)
LAST UPDATED : 199701
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C9-H6-O3
MOLECULAR WEIGHT : 162.15
WISWESSER LINE NOTATION : T66 BOVJ EQ
SYNONYMS/TRADE NAMES :
* Coumarin, 4-hydroxy-
* 4-Hydroxycoumarin
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland)
V.12-17, 1965-67. For publisher information, see PHMGBN.
Volume(issue)/page/year: 17,497,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
2,109,1946
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 750 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - muscle contraction or spasticity
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 128,126,1960
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***