*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DJ4975000
CHEMICAL NAME           : Benzo(a)pyrene, 4,5-dihydro-4,5-dihydroxy-
CAS REGISTRY NUMBER     : 28622-84-6
LAST UPDATED            : 198910
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C20-H14-O2
MOLECULAR WEIGHT        : 286.34
WISWESSER LINE NOTATION : L D6 B6666 2AB T&&T&&J LQ MQ
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Benzo(a)pyrene, 4,5-dihydroxy-4,5-dihydro-
   * BP-4,5-Dihydrodiol
   * 4,5-Dihydro-4,5-dihydroxybenzo(a)pyrene
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4580 ug/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CCSUDL Carcinogenesis--A Comprehensive Survey.  (Raven Press, 1185 Ave. of
   the Americas, New York, NY 10036)  V.1-    1976-  Volume(issue)/page/year:
   3,371,1978
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 30 umol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   41,155,1982

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: SHE-clonal assay
   
   EPA GENETOX PROGRAM 1988, Negative: Cell transform.-mouse prostate

 
                            *** END OF RECORD ***