*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DJ5020000
CHEMICAL NAME           : Benzo(a)pyrene, 9,10-dihydro-9,10-dihydroxy-, (E)-
CAS REGISTRY NUMBER     : 58886-98-9
LAST UPDATED            : 199410
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C20-H12-O2
MOLECULAR WEIGHT        : 284.32
WISWESSER LINE NOTATION : L D6 B6666 2AB T GUT&&&&J EQ FQ
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * trans-9,10-Dihydro-9,10-dihydroxybenzo(a)pyrene
   * trans-9,10-Dihydroxy-9,10-dihydrobenzo(a)pyrene
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 3500 nmol/L
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 73,607,1976
 
TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION           : 10 mg/L
REFERENCE :
   IJCNAW International Journal of Cancer.  (International Union Against
   Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland)  V.1-    1966-
   Volume(issue)/page/year: 19,814,1977
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 8 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 50,367,1978

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: In vitro SCE-nonhuman
   
   EPA GENETOX PROGRAM 1988, Negative: V79 cell culture-gene mutation
   
   EPA GENETOX PROGRAM 1988, Inconclusive: Carcinogenicity-mouse/rat;
   SHE-clonal assay
   
   EPA GENETOX PROGRAM 1988, Inconclusive: Histidine reversion-Ames test

 
                            *** END OF RECORD ***