*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DK2070000
CHEMICAL NAME           : 2H-Benzo(a)quinolizine,
                          1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-((1,2,3,4-te
                          trahydro-6,7-
                          dimethoxy-2-(2-hydroxy-3-(4-methylpiperazinyl)propyl)
                          -1-isoquinolyl)methyl )-, tetrahydrochloride
CAS REGISTRY NUMBER     : 31456-30-1
OTHER CAS REGISTRY NOS. : 26988-02-3
LAST UPDATED            : 199201
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C37-H56-N4-O5.4Cl-H
MOLECULAR WEIGHT        : 782.81
WISWESSER LINE NOTATION : T B666 GNTT&J LO1 MO1 D1- BT66 CNT&J HO1 IO1 C1YO1-
                          AT6N DNTJ &GH 4
SYNONYMS/TRADE NAMES :
   * Emetine, 2'-(2-hydroxy-3-(4-methyl-1-piperazinyl)propyl)-,  
   tetrahydrochloride
   * 2-Propanol,  
   1-(4-methyl-1-piperazinyl)-3-(6',7',10,11-tetramethoxyemetan-2'-yl)-,   4HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 14,255,1971
 
                            *** END OF RECORD ***