*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DK2175000
CHEMICAL NAME           : 2H-Benzo(a)quinolizine,
                          1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-((1,2,3,4-te
                          trahydro-6,7-
                          dimethoxy-2-(2-hydroxypropyl)-1-isoquinolyl)methyl)-,
                          dihydrochloride, isopropanol
CAS REGISTRY NUMBER     : 26987-99-5
LAST UPDATED            : 199206
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C32-H46-N2-O5.2Cl-H
MOLECULAR WEIGHT        : 611.72
WISWESSER LINE NOTATION : T B666 GNTT&J LO1 MO1 D1- BT66 CNT&J C1YQ1 HO1 IO1
                          &QY1&1 &GH 2
SYNONYMS/TRADE NAMES :
   * Emetine, 2'-(2-hydroxypropyl)-, dihydrochloride
   * 2'-(2-Hydroxypropyl)emetine dihydrochloride
   * 2-Propanol, 1-(6',7',10,11-tetramethoxyemetan-2'-yl)-, dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 14,255,1971
 
                            *** END OF RECORD ***