*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AF9172000
CHEMICAL NAME           : Acetic acid, 4-(2-chloroethyl)-2-nitrososemicarbazide
CAS REGISTRY NUMBER     : 102585-46-6
LAST UPDATED            : 198609
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C5-H9-Cl-N4-O3
MOLECULAR WEIGHT        : 208.63
WISWESSER LINE NOTATION : ONN2GVMMV1
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Acetamido-cnu
   * 1-(2-Chloroethyl)-1-nitroso-3-(methylenecarboxamido)urea
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 19700 ug/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - chronic pulmonary edema
   Gastrointestinal - ulceration or bleeding from stomach
   Blood - changes in bone marrow (not otherwise specified)
REFERENCE :
   ONCOBS Oncology.  (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.21- 
     1967-  Volume(issue)/page/year: 37,177,1980
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA damage
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 100 umol/kg
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   44,514,1984
 
                            *** END OF RECORD ***