*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AG0430000
CHEMICAL NAME           : Acetic acid, (p-chlorophenoxy)-,
                          2-(dimethylamino)ethyl ester
CAS REGISTRY NUMBER     : 51-68-3
BEILSTEIN REFERENCE NO. : 1914094
LAST UPDATED            : 199709
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C12-H16-Cl-N-O3
MOLECULAR WEIGHT        : 257.74
WISWESSER LINE NOTATION : GR DO1VO2N1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Acetic acid, (4-chlorophenoxy)-, 2-(dimethylamino)ethyl ester
   * Analux
   * ANP 235
   * At Sefen
   * Atsephen
   * Centrexin
   * Cerebon
   * Cetrexin
   * p-Chlorophenoxyacetic acid beta-dimethylaminoethyl ester
   * Clocete
   * Clofenoxin
   * Clopenoxin
   * Clophenoxate
   * Deanol p-chlorophenoxyacetate
   * Deanolestere
   * Dimethylaminoethyl-p-chlorophenoxyacetate
   * Dimethylaminoethyl-4-chlorophenoxyacetic acid
   * EN 1627
   * Licidril
   * Meclofenoxane
   * Meclofenoxate
   * Meclophenoxate
   * Mucidril
   * Proseryl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,386,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,386,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 758 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 38,154,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,386,1972
 
                            *** END OF RECORD ***