*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AG0430000 CHEMICAL NAME : Acetic acid, (p-chlorophenoxy)-, 2-(dimethylamino)ethyl ester CAS REGISTRY NUMBER : 51-68-3 BEILSTEIN REFERENCE NO. : 1914094 LAST UPDATED : 199709 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C12-H16-Cl-N-O3 MOLECULAR WEIGHT : 257.74 WISWESSER LINE NOTATION : GR DO1VO2N1&1 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Acetic acid, (4-chlorophenoxy)-, 2-(dimethylamino)ethyl ester * Analux * ANP 235 * At Sefen * Atsephen * Centrexin * Cerebon * Cetrexin * p-Chlorophenoxyacetic acid beta-dimethylaminoethyl ester * Clocete * Clofenoxin * Clopenoxin * Clophenoxate * Deanol p-chlorophenoxyacetate * Deanolestere * Dimethylaminoethyl-p-chlorophenoxyacetate * Dimethylaminoethyl-4-chlorophenoxyacetic acid * EN 1627 * Licidril * Meclofenoxane * Meclofenoxate * Meclophenoxate * Mucidril * Proseryl *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,386,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1750 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,386,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 758 mg/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 38,154,1975 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,386,1972 *** END OF RECORD ***