*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AG0525000
CHEMICAL NAME           : Acetic acid, (p-chlorophenoxy)-, 2-isopropylhydrazide
CAS REGISTRY NUMBER     : 3544-35-2
BEILSTEIN REFERENCE NO. : 2119215
LAST UPDATED            : 199801
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C11-H15-Cl-N2-O2
MOLECULAR WEIGHT        : 242.73
WISWESSER LINE NOTATION : GR DO1VMMY1&1
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Acetic acid, (4-chlorophenoxy)-, 2-(1-methylethyl)hydrazide
   * p-Chlorophenoxyacetic acid 2-isopropylhydrazide
   * 1-(p-Chlorophenoxyacetyl)-2-isopropyl hydrazine
   * Iproclozid
   * Iproclozide
   * Isopropilidrazide dell'ac. p-cloro-fenossiacetico
   * Isopropyl hydrazide de l'acide p-chlorophenoxyacetique
   * PC 603
   * PU 603
   * Sinderesin
   * SOG-4
   * Sursum
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 550 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,394,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 278 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,394,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 178 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMXXAJ French Medicament Patent Document.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Discontinued.
   Volume(issue)/page/year: #59M
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 600 mg/kg
SEX/DURATION            : female 15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
REFERENCE :
   AOGNAX Archivio di Ostetricia e Ginecologia.  (C.C. Postale N 6/19773,
   Naples, Italy)  V.1-    1894-  Volume(issue)/page/year: 71,153,1966
 
                            *** END OF RECORD ***