*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AG0572000
CHEMICAL NAME           : Acetic acid, (4-chlorophenoxy)-,
                          (1-methyl-3-piperidinyl)methyl ester, hydrochloride
CAS REGISTRY NUMBER     : 80842-08-6
LAST UPDATED            : 199406
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C15-H20-Cl-N-O3.Cl-H
MOLECULAR WEIGHT        : 334.27
WISWESSER LINE NOTATION : T6NTJ A1 C1OV1OR DG &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (4-Chlorophenoxy)acetic acid (1-methyl-3-piperidinyl)methyl ester  
   hydrochloride
   * 3-Hydroxymethyl-N-methylpiperidine (4-chlorophenoxy)acetate hydrochloride
   * 3-Piperidinemethanol, 1-methyl-, (p-chlorophenoxy)acetate, hydrochloride
   * PM 170
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 20,559,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 810 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   11,848,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 173 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   11,848,1986
 
                            *** END OF RECORD ***