*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AG1075000 CHEMICAL NAME : Acetic acid, ((p-chlorophenyl)thio)- CAS REGISTRY NUMBER : 3405-88-7 BEILSTEIN REFERENCE NO. : 1871569 REFERENCE : 4-06-00-01601 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C8-H7-Cl-O2-S MOLECULAR WEIGHT : 202.66 WISWESSER LINE NOTATION : QV1SR DG COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * p-Chlorophenylmercaptoacetic acid * ((p-Chlorophenyl)thio)acetic acid * 2-(p-Chlorophenylthio)acetic acid * SN 4095 * W 2683 * WR 5994 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,237,1946 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >400 mg/kg TOXIC EFFECTS : Behavioral - sleep Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting REFERENCE : 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,237,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1500 mg/kg/5D-I TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Related to Chronic Data - death REFERENCE : 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,237,1946 *** END OF RECORD ***