*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AG1075000
CHEMICAL NAME           : Acetic acid, ((p-chlorophenyl)thio)-
CAS REGISTRY NUMBER     : 3405-88-7
BEILSTEIN REFERENCE NO. : 1871569
REFERENCE               : 4-06-00-01601 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C8-H7-Cl-O2-S
MOLECULAR WEIGHT        : 202.66
WISWESSER LINE NOTATION : QV1SR DG
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * p-Chlorophenylmercaptoacetic acid
   * ((p-Chlorophenyl)thio)acetic acid
   * 2-(p-Chlorophenylthio)acetic acid
   * SN 4095
   * W 2683
   * WR 5994
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2
   vols., Ann Arbor, MI, J.W. Edwards, 1946  Volume(issue)/page/year:
   1,237,1946
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >400 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Gastrointestinal - hypermotility, diarrhea
   Gastrointestinal - nausea or vomiting
REFERENCE :
   85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2
   vols., Ann Arbor, MI, J.W. Edwards, 1946  Volume(issue)/page/year:
   1,237,1946
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1500 mg/kg/5D-I
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Related to Chronic Data - death
REFERENCE :
   85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2
   vols., Ann Arbor, MI, J.W. Edwards, 1946  Volume(issue)/page/year:
   1,237,1946
 
                            *** END OF RECORD ***