*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AG1170000
CHEMICAL NAME           : Acetic acid, ((p-chlorophenyl)thio)-, compd. with
                          1-oxa-4-azaspiro(4.5)decane-4-ethanol (1:1)
CAS REGISTRY NUMBER     : 87298-93-9
LAST UPDATED            : 198809
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H7-Cl-O2-S.C10-H19-N-O2
MOLECULAR WEIGHT        : 387.96
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-Oxo-4-azaspiro(4.5)decane-4-ethanol compd. with  
   ((p-chlorophenyl)thio)acetic acid (1:1)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 46,150,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 20,180,1986
 
                            *** END OF RECORD ***