*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AG2750000 CHEMICAL NAME : Acetic acid, chloro-, 2,2,2-trichloro-1-(dimethoxyphosphinyl)ethyl ester CAS REGISTRY NUMBER : 74940-61-7 OTHER CAS REGISTRY NOS. : 81406-06-6 BEILSTEIN REFERENCE NO. : 1983208 LAST UPDATED : 199806 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C6-H9-Cl4-O5-P MOLECULAR WEIGHT : 333.92 COMPOUND DESCRIPTOR : Agricultural Chemical Mutagen Reproductive Effector SYNONYMS/TRADE NAMES : * Acetic acid, chloro-, ester with dimethyl(2,2,2-trichloro-1-hydroxyethyl)phosphonate * Chloracetofon * Chloracetophon * Chloracetophone * Chloroacetic acid 2,2,2-trichloro-1-(dimethoxyphosphinyl)ethyl ester * O,O-Dimethyl (2,2,2-trichloro-1-(chloroacetoxy)ethyl)phosphonate *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 344 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GNKAA5 Genetika (Moscow). For English translation, see SOGEBZ. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1965- Volume(issue)/page/year: 22,2540,1986 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 421 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,203,1990 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 200 mg/kg SEX/DURATION : female 13 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : EKMMA8 Eksperimentalna Meditsina i Morfologiya. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1962- Volume(issue)/page/year: 23,201,1984 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 168 mg/kg SEX/DURATION : female 1-21 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - delayed effects REFERENCE : KHZDAN Khigiena i Zdraveopazvane. Hygiene and Sanitation. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.9- 1966- Volume(issue)/page/year: 26,297,1983 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 2 mg/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,203,1990 TYPE OF TEST : Micronucleus test ROUTE OF EXPOSURE : Unreported TEST SYSTEM : Rodent - hamster DOSE/DURATION : 60 mg/kg REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,203,1990 TYPE OF TEST : Mutation test systems - not otherwise specified ROUTE OF EXPOSURE : Unreported TEST SYSTEM : Rodent - hamster DOSE/DURATION : 42 mg/kg REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,203,1990 *** END OF RECORD ***