*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AG3675000
CHEMICAL NAME           : Acetic acid, cyano-
CAS REGISTRY NUMBER     : 372-09-8
BEILSTEIN REFERENCE NO. : 0506325
REFERENCE               : 4-02-00-01888 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C3-H3-N-O2
MOLECULAR WEIGHT        : 85.07
WISWESSER LINE NOTATION : QV1CN
SYNONYMS/TRADE NAMES :
   * Acide cyanacetique
   * Cyanessigsaeure
   * Cyanoacetic acid
   * Kyselina kyanoctova
   * Malonic mononitrile
   * Monocyanoacetic acid
   * USAF KF-17
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - dyspnea
   Skin and Appendages - hair
REFERENCE :
   LONZA# Personal Communication from LONZA Ltd., CH-4002, Basel, Switzerland
   Volume(issue)/page/year: 12JAN1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD691-490
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1900 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Lungs, Thorax, or Respiration - respiratory depression
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 5,161,1899
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 1300 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 5,161,1899

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4050
       No. of Facilities: 17 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 919 (estimated)
       No. of Female Employees: 306 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8842
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***