*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : AG4110000
CHEMICAL NAME : Acetic acid, cyano-, ethyl ester
CAS REGISTRY NUMBER : 105-56-6
BEILSTEIN REFERENCE NO. : 0605871
REFERENCE : 4-02-00-01889 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 9
MOLECULAR FORMULA : C5-H7-N-O2
MOLECULAR WEIGHT : 113.13
WISWESSER LINE NOTATION : NC1VO2
SYNONYMS/TRADE NAMES :
* Cyanacetate ethyle
* Cyanoacetic acid ethyl ester
* Cyanoacetic ester
* Estere cianoacetico
* Ethyl cyanoethanoate
* Ethylester kyseliny kyanoctove
* Malonic acid ethyl ester nitrile
* USAF KF-25
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,921,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: AD277-689
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1410 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory
change
Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 5,161,1899
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 1115 mg/kg
TOXIC EFFECTS :
Behavioral - tremor
Behavioral - muscle contraction or spasticity
Gastrointestinal - nausea or vomiting
REFERENCE :
MELAAD Medicina del Lavoro. Industrial Medicine. (Via S. Barnaba, 8, 20122
Milan, Italy) V.16- 1925- Volume(issue)/page/year: 47,192,1956
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Amphibian - frog
DOSE/DURATION : 4200 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory
change
Behavioral - tremor
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 5,161,1899
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 83848
No. of Facilities: 21 (estimated)
No. of Industries: 1
No. of Occupations: 2
No. of Employees: 62 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 83848
No. of Facilities: 17 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 425 (estimated)
No. of Female Employees: 17 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***