*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AH1010000 CHEMICAL NAME : Acetic acid, (2-dimethylaminoethoxy)diphenyl-, ethyl ester LAST UPDATED : 198405 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H25-N-O3 MOLECULAR WEIGHT : 327.46 COMPOUND DESCRIPTOR : Drug Primary Irritant SYNONYMS/TRADE NAMES : * D-401 * (2-Dimethylaminoethoxy)diphenylacetic acid ethyl ester * Ethyl alpha-(beta-dimethylaminoethoxy)diphenylacetate *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 5000 ppm/3M REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 44,743,1955 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 57 mg/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Behavioral - excitement REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 44,743,1955 *** END OF RECORD ***