*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AH2790000 CHEMICAL NAME : Acetic acid, 2,2-diphenyl-2-ethoxy-, (2-(dimethylamino)ethyl) ester, hydrochloride CAS REGISTRY NUMBER : 2424-75-1 LAST UPDATED : 199012 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C20-H25-N-O3.Cl-H MOLECULAR WEIGHT : 363.92 WISWESSER LINE NOTATION : 2OXR&R&VO2N1&1 &GH COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Acetic acid, ethoxydiphenyl-, 2-(dimethylamino)ethyl ester hydrochloride * Aestocin * Benzeneacetic acid, alpha-ethoxy-alpha-phenyl-, 2-(dimethylamino)ethyl ester hydrochloride * Dimenoxadol hydrochloride * Dimethylaminoethyl-diphenylethoxy acetate hydrochloride * beta'-Dimethylaminoethyl-alpha,alpha-diphenyl-alpha-ethoxyacetate hydrochloride * 2,2-Diphenyl-2-ethoxyacetic acid (2-(dimethylamino)ethyl) ester hydrochloride * Estocin * Estocine * Estotsin * Lokarin * Propalgyl *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 66 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 8,189,1974 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 175 mg/kg TOXIC EFFECTS : Behavioral - analgesia REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 4,7,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 179 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 32,317,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 40 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,571,1965 *** END OF RECORD ***