*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AH2975000 CHEMICAL NAME : Acetic acid, diphenyl-, 1-ethyl-3-piperidyl ester, hydrochloride CAS REGISTRY NUMBER : 129-77-1 LAST UPDATED : 199603 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C21-H25-N-O2.Cl-H MOLECULAR WEIGHT : 359.93 WISWESSER LINE NOTATION : T6NTJ A2 COVYR&R &GH COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * AN 1087 * Benzeneacetic acid, alpha-phenyl-, 1-ethyl-3-piperidinyl ester, hydrochloride * Benzeneacetic acid, alpha-phenyl-, 1-ethyl-3-piperidyl ester, hydrochloride * Dactil hydrochloride * Diphenylacetic acid, 1-ethyl-3-piperidyl ester hydrochloride * N-Ethyl-3-piperidyl diphenylacetate hydrochloride * 1-Ethyl-3-piperidyl diphenyl-acetate hydrochloride * 3-Piperidinol, 1-ethyl-, diphenylacetate, hydrochloride * Piperidolate hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 19 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,97,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1040 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada) TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 26 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 104,269,1952 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 35 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,97,1969 *** END OF RECORD ***