*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DL0525000
CHEMICAL NAME           : 1,5-Benzothiazepin-4(5H)-one,
                          5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-phenyl-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 3122-01-8
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H22-N2-O-S.Cl-H
MOLECULAR WEIGHT        : 362.95
WISWESSER LINE NOTATION : T67 GNV KS&TJ G2N1&1 JR &GH
SYNONYMS/TRADE NAMES :
   * Altinil
   *   5-(2-Dimethylaminoethyl)-2,3-dihydro-2-phenyl-1,5-benzothiazepin-4-(5H)-
     one hydrochloride
   * SQ 10496
   * Thiazesim hydrochloride
   * Thiazesium hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,310,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 29 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,310,1972
 
                            *** END OF RECORD ***