*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DL0710500
CHEMICAL NAME           : 2H-1,2-Benzothiazine-3-carboxamide,
                          4-hydroxy-2-methyl-N-2-thiazolyl-, 1,1-dioxide
CAS REGISTRY NUMBER     : 34042-85-8
BEILSTEIN REFERENCE NO. : 0628704
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H11-N3-O4-S2
MOLECULAR WEIGHT        : 337.39
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * CP 15973
   * 4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide  
   1,1-dioxide
   * Sudoxicam
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 136 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 28,1714,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 260 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,848,1972
 
                            *** END OF RECORD ***