*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DL4900000
CHEMICAL NAME           : Benzothiazole, 2-(2-hydroxyethylthio)-
CAS REGISTRY NUMBER     : 4665-63-8
LAST UPDATED            : 199309
DATA ITEMS CITED        : 3
WISWESSER LINE NOTATION : T56 BN DSJ CS2Q
SYNONYMS/TRADE NAMES :
   * HMBT
   * 2-(2-Hydroxyethylmercapto)benzothiazole
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1017 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Vascular - regional or general arteriolar or venous dilation
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   14,221,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 417 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Vascular - regional or general arteriolar or venous dilation
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   14,221,1969
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 728 mg/kg/7D-I
TOXIC EFFECTS :
   Liver - liver function tests impaired
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   14,221,1969
 
                            *** END OF RECORD ***