*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DN6825000
CHEMICAL NAME           : Benzyl alcohol, alpha-aminomethyl-2,5-dimethoxy-,
                          hydrochloride
CAS REGISTRY NUMBER     : 60407-53-6
LAST UPDATED            : 199303
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H15-N-O3.Cl-H
MOLECULAR WEIGHT        : 233.72
WISWESSER LINE NOTATION : Z1YQR BO1 EO1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * alpha-(Aminomethyl)-2,5-dimethoxybenzyl alcohol hydrochloride
   * 1-(2',5'-Dimethoxyphenyl)-2-aminoethanol hydrochloride
   * beta-(2,5-Dimethoxyphenyl)-beta-hydroxyethylamine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1470 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Behavioral - convulsions or effect on seizure threshold
   Skin and Appendages - hair
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 21,529,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 131 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - somnolence (general depressed activity)
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 92,283,1948
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3770 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - stiffness
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 21,529,1987
 
                            *** END OF RECORD ***