*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DO2450000
CHEMICAL NAME           : Benzyl alcohol,
                          3,4-dihydroxy-alpha-(1-(methylamino)ethyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 946-43-0
LAST UPDATED            : 199009
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H15-N-O3.Cl-H
MOLECULAR WEIGHT        : 233.72
WISWESSER LINE NOTATION : QR BQ DYQY1&M1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3,4-Dihydroxyephedrine hydrochloride
   * Dioxy-ephedrin
   * 3,4-Dioxyephedrine
   * 1-Propanol, 1-(3,4-dihydroxyphenyl)-2-methylamino-, hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 71,62,1941
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,103,1948

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   CHREAY Chemical Reviews.  (American Chemical Soc., Distribution Office Dept.
   223, POB 57136, West End Stn., Washington, DC 20037)  V.1-    1924-
   Volume(issue)/page/year: 9,389,1931

 
                            *** END OF RECORD ***