*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DO7350000 CHEMICAL NAME : Benzyl alcohol, p-hydroxy-alpha-((methylamino)methyl)- CAS REGISTRY NUMBER : 94-07-5 LAST UPDATED : 199601 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C9-H13-N-O2 MOLECULAR WEIGHT : 167.23 WISWESSER LINE NOTATION : QR DYQ1M1 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Analeptin * Ethaphene * 4-Hydroxy-alpha-((methylamino)methyl)benzenemethanol * p-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol * p-Hydroxyphenylmethylaminoethanol * 1-(4-Hydroxyphenyl)-2-methylaminoethanol * 1-(4-Hydroxyphenyl)-N-methylethanolamine * p-Methylaminoethanolphenol * beta-Methylamino-alpha-(4-hydroxyphenyl)ethyl alcohol * Methylaminomethyl(4-hydroxyphenyl)carbinol * Oxedrine * p-Oxedrine * alpha-(4-Oxyphenyl)alpha-oxy-beta-methylaminoaethan * Parakorper * Parasympatol * Pentedrin * S 38537-9 * Simpalon * Simpatol * Sympathol * Synefrin * Synephrin * Synephrine * p-Synephrine * Synthenate *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 101,81,1955 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 89,297,1947 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1500 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 136,172,1928 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 270 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 106,341,1952 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 101,81,1955 *** END OF RECORD ***