*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DP1050000 CHEMICAL NAME : Benzyl alcohol, alpha-((2-pyridylamino)methyl)- CAS REGISTRY NUMBER : 553-69-5 BEILSTEIN REFERENCE NO. : 0169969 REFERENCE : 5-22-08-00301 (Beilstein Handbook Reference) LAST UPDATED : 199706 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C13-H14-N2-O MOLECULAR WEIGHT : 214.29 WISWESSER LINE NOTATION : T6NJ BM1YQR COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Benzenemethanol, alpha-((2-pyridinylamino)methyl)- * Bonapar * Cabral * Evasprine * Fenyramidol * Fenyripol * 2-(beta-Hydroxyphenethylamino)pyridine * IN 511 * MJ 505 * Phenyramidol * alpha-(2-Pyridylaminomethyl)benzyl alcohol *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 756 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 130,280,1961 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1850 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 103,245,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 355 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 141,83,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 405 mg/kg TOXIC EFFECTS : Behavioral - anticonvulsant REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 19,247,1962 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 124 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 141,83,1963 *** END OF RECORD ***