*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DP1575000
CHEMICAL NAME           : Benzylamine, N,N-bis(2-chloroethyl)-
CAS REGISTRY NUMBER     : 55-51-6
BEILSTEIN REFERENCE NO. : 2099546
REFERENCE               : 4-12-00-02164 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C11-H15-Cl2-N
MOLECULAR WEIGHT        : 232.17
WISWESSER LINE NOTATION : G2N2G1R
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Benzenemethanamine, N,N-bis(2-chloroethyl)-
   * Benzylbis(beta-chloroethyl)amine
   * Benzyl nor-mechlorethamine
   * N,N-Bis(2-chloroethyl)benzenemethanamine
   * Bis(2-chloroethyl)benzylamine
   * N,N-Bis(2-chloroethyl)benzylamine
   * DCBA
   * Di-(2-chloroethyl)-benzylamine
   * TL 695
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHBUA9 Pharmaceutical Bulletin.  (Tokyo, Japan)  V.1-5, 1953-57.  For
   publisher information, see CPBTAL.  Volume(issue)/page/year: 1,297,1953
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NDRC** National Defense Research Committee, Office of Scientific Research
   and Development, Progress Report.  Volume(issue)/page/year: No.9-4-1-9,1943
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 2500 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 14,115,1972
 
TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Intravaginal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 5000 ppm
REFERENCE :
   JIDEAE Journal of Investigative Dermatology.  (Williams & Wilkins Co., 428
   E. Preston St., Baltimore, MD 21202)  V.1-    1938- Volume(issue)/page/year:
   62,378,1974

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: Aspergillus-reversion

 
                            *** END OF RECORD ***