*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DP1603000
CHEMICAL NAME           : Benzylamine, N,N-bis(2-chloroethyl)-, N-oxide,
                          hydrochloride
CAS REGISTRY NUMBER     : 99858-23-8
LAST UPDATED            : 198803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H15-Cl2-N-O.Cl-H
MOLECULAR WEIGHT        : 284.63
WISWESSER LINE NOTATION : G2KO&2G1R &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N,N-Bis(2-chloroethyl)benzylamine N-oxide hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 33 mg/kg
TOXIC EFFECTS :
   Blood - leukopenia
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 8,89,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 114 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   53,190,1957
 
                            *** END OF RECORD ***