*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DR9808500
CHEMICAL NAME           : Berbine,
                          13,13a-didehydro-9,10-dimethoxy-2,3-(methylenedioxy)-
CAS REGISTRY NUMBER     : 483-15-8
BEILSTEIN REFERENCE NO. : 0344128
REFERENCE               : 4-27-00-06505 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H19-N-O4
MOLECULAR WEIGHT        : 337.40
WISWESSER LINE NOTATION : T G6 E6 B665 EN SO UO FH TH&&T&&J HO1 IO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6H-Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizine,  
   5,8-dihydro-9,10-dimethoxy-
   * Berberine, dihydro-
   * Dihydroberbine
   * 7,8-Dihydroberberine
   * Dihydroumbellatine
   * 9,10-Dimethoxy-2,3-(methylenedioxy)-13,13a-didehydroberbine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 190 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,486,1981
 
                            *** END OF RECORD ***