*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DR9810000
CHEMICAL NAME           : 13a-alpha-Berbine, 2,3,10,11-tetramethoxy-, citrate
LAST UPDATED            : 198406
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H25-N-O4.C6-H8-O7
MOLECULAR WEIGHT        : 547.61
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6H-Dibenzo(a,g)quinolizine,  
   5,8,13,13a-tetrahydro-2,3,10,11-tetramethoxy-, citrate, (S)-
   * Govanine methyl ether citrate
   * O-Methylgovanine citrate
   * Norcoralydine citrate
   * 2,3,10,11-Tetramethoxy-13a-alpha-berbine citrate
   * Xylopinine citrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 71500 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JJPAAZ Japanese Journal of Pharmacology.  (Japanese Pharmacological Soc.,
   c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto
   606, Japan)  V.1-    1951-  Volume(issue)/page/year: 12,208,1962
 
                            *** END OF RECORD ***