*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DR9840000
CHEMICAL NAME           : Berbine, 2,3,9,10-tetramethoxy-, hydrochloride, (+-)-
CAS REGISTRY NUMBER     : 6024-85-7
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H25-N-O4.Cl-H
MOLECULAR WEIGHT        : 391.93
WISWESSER LINE NOTATION : T D6 B666 KN&TT&J GO1 HO1 PO1 QO1 &GH
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * Palmatine, tetrahydro-, hydrochloride, (+-)-
   * dl-Tetrahydropalmatine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 17,30,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 121500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 5,163,1946
 
                            *** END OF RECORD ***