*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DR9859000
CHEMICAL NAME           : Berbinium,
                          7,7'-(((2-methylthiazolidin-3-yl)phosphinylidene)bis(
                          iminomethylene))bis(9 ,10-
                          dimethoxy-2,3-(methylenedioxy)-5,6,13,13a-tetradehydr
                          o-
LAST UPDATED            : 198212
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C48-H52-N5-O9-P-S
MOLECULAR WEIGHT        : 906.08
WISWESSER LINE NOTATION : T F5 D6 C666 GO IO OK HH PHJ RO1 SO1 O2MPO&- AT5N
                          CSTJ B1&M2- OT
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N',N''-Di-(N-berberinylethylamide) of  
   2'-methylthiazolidin-3-yl-phosphoric acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 68 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,486,1981
 
                            *** END OF RECORD ***