*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DR9866000
CHEMICAL NAME           : Berbinium,
                          5,6,13,13a-tetradehydro-7-(2-((di(1-aziridinyl)thioph
                          osphinyl)amino)ethyl) -9,10-
                          dimethoxy-2,3-(methylenedioxy)-
LAST UPDATED            : 198212
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C26-H32-N4-O4-P-S
MOLECULAR WEIGHT        : 527.65
WISWESSER LINE NOTATION : T F5 D6 C666 GO IO OK HH PHJ RO1 SO1 O2MPS&- AT3NTJ&-
                          AT3NTJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Mono-N'-(2-(N-berberinyl)ethylamide) of diaziridinylthiophosphoric acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,486,1981
 
                            *** END OF RECORD ***