*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DR9866300
CHEMICAL NAME           : Berbinium,
                          5,6,13,13a-tetradehydro-7-(5-((di(1-aziridinyl)thioph
                          osphinyl)amino)-2-
                          oxopentyl)-9,10-dimethoxy-2,3-(methylenedioxy)-
LAST UPDATED            : 198212
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C29-H34-N4-O5-P-S
MOLECULAR WEIGHT        : 581.70
WISWESSER LINE NOTATION : T F5 D6 C666 HO JO OK IH PHJ SO1 TO1 P1V3MPS&-
                          AT3NTJ&- AT3NTJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N'-(2-(Acetonylberberinyl)ethylamide) of diaziridinylthiophosphoric acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4200 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,486,1981
 
                            *** END OF RECORD ***