*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DT4391200
CHEMICAL NAME : Bibenzyl-4,4'-diol,
alpha,alpha'-diethyl-alpha,alpha'-epoxy-
CAS REGISTRY NUMBER : 6052-82-0
BEILSTEIN REFERENCE NO. : 0030889
REFERENCE : 4-17-00-02197 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C18-H20-O3
MOLECULAR WEIGHT : 284.38
WISWESSER LINE NOTATION : T3OTJ B2 BR DQ& C2 CR DQ
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* DES-alpha,beta-oxide
* DES 3,4-oxide
* alpha,alpha'-Diethyl-alpha,alpha'-epoxybibenzyl-4,4'-diol
* Diethylstilboestrol-alpha,beta-oxide
* Diethylstilboestrol-3,4-oxide
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - hamster
DOSE/DURATION : 640 mg/kg/38W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
43,5200,1983
** MUTATION DATA **
TYPE OF TEST : DNA damage
TEST SYSTEM : Human Leukocyte
DOSE/DURATION : 300 umol/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
34,3251,1985
TYPE OF TEST : Sister chromatid exchange
TEST SYSTEM : Human Fibroblast
DOSE/DURATION : 40 nmol/L
REFERENCE :
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
V.1- 1869- Volume(issue)/page/year: 281,392,1979
*** END OF RECORD ***