*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DT8400000 CHEMICAL NAME : Bicyclo(7.2.0)undec-4-ene, 8-methylene-4,11,11-trimethyl-, (E)-(1R,9S)-(-)- CAS REGISTRY NUMBER : 87-44-5 LAST UPDATED : 199712 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C15-H24 MOLECULAR WEIGHT : 204.39 WISWESSER LINE NOTATION : L49 EY HUTJ B1 B1 EU1 I1 COMPOUND DESCRIPTOR : Natural Product Primary Irritant SYNONYMS/TRADE NAMES : * Bicyclo(7.2.0)undec-4-ene, 4,11,11-trimethyl-8-methylene-, (1R-(1R*,4E,9S*))- * beta-Caryophyllen * Caryophyllene * (-)-Caryophyllene * beta-Caryophyllene * l-Caryophyllene * trans-Caryophyllene * 8-Methylene-4,11,11-(trimethyl)bicyclo(7.2.0)undec-4-ene *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 500 mg/24H REFERENCE : FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,1059,1973 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intratracheal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >48 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - pulmonary emboli REFERENCE : ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 59,78,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7407 No. of Facilities: 3144 (estimated) No. of Industries: 10 No. of Occupations: 18 No. of Employees: 44746 (estimated) No. of Female Employees: 27262 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***