*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DT8400000
CHEMICAL NAME           : Bicyclo(7.2.0)undec-4-ene,
                          8-methylene-4,11,11-trimethyl-, (E)-(1R,9S)-(-)-
CAS REGISTRY NUMBER     : 87-44-5
LAST UPDATED            : 199712
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C15-H24
MOLECULAR WEIGHT        : 204.39
WISWESSER LINE NOTATION : L49 EY HUTJ B1 B1 EU1 I1
COMPOUND DESCRIPTOR     : Natural Product
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Bicyclo(7.2.0)undec-4-ene, 4,11,11-trimethyl-8-methylene-,  
   (1R-(1R*,4E,9S*))-
   * beta-Caryophyllen
   * Caryophyllene
   * (-)-Caryophyllene
   * beta-Caryophyllene
   * l-Caryophyllene
   * trans-Caryophyllene
   * 8-Methylene-4,11,11-(trimethyl)bicyclo(7.2.0)undec-4-ene
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 11,1059,1973
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intratracheal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >48 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - pulmonary emboli
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   59,78,1986

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X7407
       No. of Facilities: 3144 (estimated)
       No. of Industries: 10
       No. of Occupations: 18
       No. of Employees: 44746 (estimated)
       No. of Female Employees: 27262 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***