*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DU2076000
CHEMICAL NAME           : Biguanide, 1-(p-((p-nitrophenyl)sulfonyl)phenyl)-
CAS REGISTRY NUMBER     : 20566-98-7
BEILSTEIN REFERENCE NO. : 2183364
REFERENCE               : 3-13-00-01308 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H14-N6-O4-S
MOLECULAR WEIGHT        : 362.40
WISWESSER LINE NOTATION : WNR DSWR DMYUM&MYZUM
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(p-((p-Nitrophenyl)sulfonyl)phenyl)biguanide
   * T-1214
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 12,336,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 165 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPFAR Acta Poloniae Pharmaceutica (English Translation).  Translation of
   APPHAX.  (Warsaw, Poland) V.20-29, 1963-72.  Discontinued.
   Volume(issue)/page/year: 26,487,1969
 
                            *** END OF RECORD ***